Three’s company

I’ll jump to the punchline and let you know that Dr. Y got all three eggs!

Here’s a breakdown of the day:

6:15 am – Woke up & showered…but skipped deodorant, lotion, or anything scented. (Apparently perfume is not good for eggs.)

7:23 am – Checked in at the surgery center with C.

8:00 am – Got IV sedative placed. Lights out.

~9:30 am – Woke up with a slight headache and waited a long time for C’s chance to give his sample. (Apparently the “collection room” got backed up…)

~10:45 am – The embryologist came by and gave us the egg report. She said one egg is “mature” and two are “intermediate”. She said that there’s a “good chance” that one of the two intermediate eggs will mature today in time for intracytoplasmic sperm injection (ICSI). She also told us that they’ll be growing our embryos in coculture with some cumulus cells from my ovaries (a technique called cumulus coculture). This is supposed to “detoxify” the medium that the embies are growing in, and provide some growth factors to help my embryos grow better.

11 am – “Collection room” finally free. C did his part.

11:30 am – Headed home.

In summary, we got pretty much the best result we could hope for at this point, given how things looked going in. Now we just pray that they all fertilize and grow.

Stay tuned for tomorrow’s fertilization report!

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Catching up

Today’s ultrasound went better than Monday’s. Dr. Y seemed much more upbeat. Lefty is at 22 mm, with Righty catching up at 17 mm. The third follicle has also been growing, and is now at 12 mm. Dr. Y said it could grow enough before retrieval to be good, but the chance of this is definitely less than for the other two. My estradiol was at 781 (whatever that means…)

The net result is that we’ll trigger tonight at 9:30, with egg retrieval scheduled for 7:30 on Friday morning!

Given the fact that we have only two good-looking follicles, Dr. Y explained a few special precautions he’s taking with the retrieval.

First, he added another drug called indomethacin.

ImageIndomethacin is a non-steroidal anti inflammatory drug (NSAID) that apparently is also useful for preventing ovulation. Dr. Y said this would be extra insurance (in addition to the ganirelix) to make sure that Lefty waits around until Saturday.

Second, he said he’ll use a double lumen needle in place of the usual single lumen one. Dr. Google informs me that the double lumen needle looks like a needle within a needle:

ImageI think the inner (bigger) hole is used to aspirate up the egg (like with a single lumen needle), but the double lumen needle has the added functionality of being able to squirt water from the outer hole into the follicle and ‘rinse’ it out. The rinse can be aspirated out again to catch the egg if it wasn’t sucked up the first time.

Dr. Y seemed to think we have a good chance of retrieving the two big eggs. Either way, he said he will be able to tell us how many he got immediately after surgery. (C is not looking forward to the responsibility of being first to know the news…) If we get something on Friday, then we’ll find out on Saturday whether it/they fertilized. And if something fertilizes, then we’ll find out on Monday whether it survived to Day 3 for freezing. Given the small number of follicles, Dr. Y doubts that we would risk letting them grow to Day 5, but he didn’t rule it out completely.

So today is my last day of stims, ganirelix, dexamethasone, aspirin and prenatals. I’m also supposed to do a Follistim ‘boost’ tonight right after C gives me my hCG trigger shot at 9:30 tonight. That makes a total of 5 shots today! Tomorrow I continue the indomethacin and growth hormone (which I haven’t written anything about yet…sorry!)

Here’s an updated version of my protocol that reflects the adjustments:

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